Scottish scientists have developed a low-cost, flexible device that can help prevent blood clots for patients after an operation.
Their polymer-based sensor fits underneath bandages and compression stockings like a sticking plaster, and a handheld reader measures whether the bandage is exerting the correct pressure on the body.
The body’s circulatory system relies on blood return from the heart, but also on muscular activity. Compression therapies such as stockings exert a gentle gradient pressure on the body to support blood flow while someone is immobilised.
This helps to prevent blood clots such as deep vein thrombosis (DVT) and reduces pain and swelling for people with lymphedema, but currently pressure exerted by commercially available compression garments is poorly controlled and difficult to measure.
Badly fitting stockings are either ineffective, in that they don’t help prevent DVT, or, if the pressure is incorrect, they can reduce blood flow and even raise the chances of an embolism or blood clot.
The sensor, invented by Dr Philip Hands (pictured) of the University of Edinburgh alongside Professor Marc Desmulliez and Drs Vasileios Mitrakos and Lisa Macintyre of Heriot-Watt University, is wireless, thinner, more sensitive and more flexible than similar devices, so it doesn’t distort the compression garment as it measures the pressure.
The team has received £75k of Scottish Enterprise High Growth Spinout funding, as they move towards forming a company, supported by Edinburgh Innovations, the University of Edinburgh’s commercialisation service.
Dr Hands, of Edinburgh’s School of Engineering, said: “Currently most people who have an operation wake up to find themselves wearing compression stockings, and often they don’t fit well. Our device is unobtrusive, and with a wave of the handheld antennae near the body you can measure the pressure and adjust the stocking or bandage. We think this simple, cheap device has huge potential.
“Existing sensors are bulky and have protruding wires that can damage the skin. At the Scottish Microelectronics Centre (SMC) in Edinburgh we have developed a method of manufacture that outperforms other devices due to our sensor’s low cost, high precision and ultra flexibility.”
Professor Desmulliez, Associate Principal (Impact) at Heriot-Watt University, said: “Due to its polymer composition, the sensor offers versatility as one or more can be positioned anywhere on the body. It could also have broader applications in all sorts of wearable devices, roll up smartphones, and high-performance sports equipment, such as elite swimsuits, where fit is extremely important.”
Ian Hatch, Edinburgh Innovations’ Head of Business Development for the College of Science and Engineering, said: “We’re excited about this technology and looking for clinical partners in the fields of medicine and sport to engage in co-development and/or trials. We also welcome the opportunity to work with supply chain partners to scale up manufacturing and delivery. We see this as an ideal opportunity for investors.”
Funders so far include Innovate UK’s ICURe programme, a PhD studentship funded by Heriot-Watt University through the Edinburgh Research Partnership in Engineering, a grant from the EPSRC-NIHR HTC Partnership Award: MDVSNPLUS, and a joint award by the EPSRC Impact Acceleration Accounts at the University of Edinburgh and Heriot-Watt University.
